People who are at higher risk for developing latex allergy include: Health care workers and others who frequently wear latex gloves. People who have had multiple surgeries (for example, 10 or more), such as children with spina bifida. People who are often exposed to natural rubber latex, including rubber industry workers.

There are different levels of latex allergy. The mildest version shows up in the vagina or on the penis as itching, red skin and hives, or a rash. More severe symptoms include difficulty breathing, coughing and wheezing, sneezing, a runny nose, itchy eyes, or a scratchy throat.