In November 2013 the American Council on Science and Health ridiculed Scientific American for publishing junk science.1 ACSH alleged that SA “looked like imbeciles” for publishing the study, “Mice Harmed by Low Dose of BPA, Not High” (July 25, 2013 issue of SA). ACSH’s Dr. Bloom asserts that it is “crazy” for anyone to believe that a small dose of a chemical can cause harm while a large dose will not.
Call me crazy, but it is possible. In February 2012 ISHN published my article, “Endocrine Disrupting Chemicals pose challenges: Many EDCs are harmful at low doses and safe at high doses.”2 I based the article upon a review of the evolving science including “Endocrine-Disrupting Chemicals: An Endocrine Society Scientific Statement” (2009).3 As a CIH with graduate studies in toxicology, I understand that nontraditional inverted-U or U-shaped dose-response curves, which gives rise to dose dilemmas, are scientifically valid.