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Nano-safety studies urged in China

September 25, 2012
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nanoparticlesChina should carry out more-extensive safety studies and improve regulatory oversight of synthetic nanomaterials, leading Chinese researchers said at the 6th International Conference on Nanotoxicology in Beijing this month.

“This is the only way to maintain the competitiveness of China’s nanotechnology sector,” says Zhao Yuliang, deputy director of the Chinese Academy of Sciences’ National Center for Nano­science and Technology (NCNST) in Beijing. “We certainly don’t want safety issues to become a trade barrier for nano-based products.”

China’s investment in nanotechnology has grown rapidly during the past decade, and its tally of patent applications in the field has surpassed those of Europe and the United States. But only 3% of the investment is used for safety studies, says Zhao, compared with about 6% of federal nanotechnology funding in the United States.

Researchers at the meeting said that better safety testing was needed for products containing nanoparticles that can be absorbed by the body, such as food and cosmetics in which nanoparticles provide specific colours or textures. But occupational exposure among workers handling the materials may present the greatest risks: China’s workplace safety rules are not always implemented, and they set no specific limits for handling nanoparticles.

Chinese researchers will next year join forces with colleagues in Europe, the United States and Brazil in a €13-million project called Nanosolutions, to develop a nano-safety classification system based on material characteristics, toxicity studies and bioinformatics data. Initially focusing on 30 or so materials, such as carbon nanotubes, and nanoparticles of titanium dioxide and silver, the team will use high-throughput screening to identify the most toxic, and then investigate their biological effects in animal studies.

The data will be used to develop computer software to predict the potential hazards of other nanomaterials.

Studying factory workers who are exposed to nanomaterials could yield further insights. With Chinese exposure levels likely to be much higher than those in Western factories, such surveys are ideally placed to quantify the risks involved, says Dhimiter Bello, an expert in occupational health at the University of Massachusetts in Lowell. Since last year, a team led by the NCNST’s Chen Chunying has been monitoring chemical exposure levels, including those of nanomaterials, in three factories that have varying safety practices. The researchers hope that their data will help the government to draw up regulations covering nanoparticles in the workplace.

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