Today's News / Health

Caffeine consumption can improve treatment of dry eye

April 25, 2012
/ Print / Reprints /
ShareMore
/ Text Size+

caffeine may affect eye healthResearchers at the University of Tokyo's School of Medicine have shown for the first time that caffeine intake can significantly increase the eye's ability to produce tears, a finding that could improve treatment of dry eye syndrome. This common eye condition affects about four million people age 50 and older in the United States. For many, dry eye syndrome is simply uncomfortable and annoying, but for others it escalates into a vision-threatening disease.

All of the 78 participants in the new study produced significantly more tears after consuming caffeine than after taking a placebo. The study is available in Ophthalmology, the journal of the American Academy of Ophthalmology.

Dry eye syndrome involves malfunction of the rate of tear production, the quality of tears, and/or the rate of evaporate from the surface of the eye. Anyone can experience dry eye, though it is more common among women. Symptoms can include gritty, scratchy or burning sensations, excessive tearing, and/or production of stringy mucus.

The research team, by Reiko Arita, MD, PhD, was motivated by an earlier study that had shown a reduced risk for dry eye in caffeine users: 13 percent of users had the syndrome compared with nearly 17 percent of non-users. The team knew that caffeine was likely to stimulate tear glands, since it is known to increase other secretions, such as saliva and digestive juices. They also knew that people respond differently to caffeine, so they analyzed study participants' DNA samples for two genetic variations that play important roles in caffeine metabolism. Tear production proved to be higher in study subjects who had the two genetic variations.

"If confirmed by other studies, our findings on caffeine should be useful in treating dry eye syndrome," said Dr. Arita. "At this point, though, we would advise using it selectively for patients who are most sensitive to caffeine's stimulating effects."

The study subjects were divided into two groups: one received caffeine tablets in the first session and a placebo in the second session, while the order was reversed for the other group. Tear volume was measured within 45 minutes of consuming the tablets. All sessions took place between 10 a.m. and noon, a time of day when tear production is usually stable. No subjects knew whether they received caffeine or the placebo. All abstained from caffeine use for six days prior to each session and used no drugs during the sessions. To be eligible for the study subjects had to be free of high blood pressure, dry eye syndrome, allergies that affect the eye, glaucoma, and other eye diseases and conditions that can interfere with tear production. The study also found that tear drainage rates were not affected by caffeine.

Dry eye can be very uncomfortable and interfere with vision. It's important to see an ophthalmologist if symptoms continue, since advanced cases can cause eye damage and permanent vision problems. Current treatment options range from simple warm compresses, eye washes and artificial tears to medications and tear drainage devices.

Did you enjoy this article? Click here to subscribe to ISHN.

You must login or register in order to post a comment.

Multimedia

Videos

Image Galleries

Scenes from the World of Safety

Sights, signs & symbols from the National Safety Congress & Expo held in San Diego, CA, September 15-18

11/4/14 2:00 pm EST

Eye Injuries: You rarely see them coming. Practical Solutions for reducing injuries to the eye.

The 3M Eye Injury Reduction webinar will provide an examination of how to help solve eye injuries in the workplace. This issue continues to challenge virtually every industry, and the solution is often times multifaceted. 3M will share some new tools and approaches to help you in solving this issue.

ISHN Magazine

ISHN1014_cover.jpg

2014 October

This issue features articles about PPE safety and OSHA standards

Table Of Contents Subscribe

THE ISHN STORE

M:\General Shared\__AEC Store Katie Z\AEC Store\Images\ISHN\safetyfourth.jpg
Safety Engineering, 4th Edition

A practical, solutions-driven reference, Safety Engineering, 4th edition, has been completely revised and updated to reflect many of today’s issues in safety.

More Products

For Distributors Only - SEPTEMBER 2014

ISHN FDO SEPTEMBER 2014For Distributors Only is ISHN's niche brand standard-sized magazine supplement aimed at an audience of 2,000 U.S. distributors that sell safety products. Circulation only goes to distributors. CHECK OUT THE SEPTEMBER 2014 ISSUE OF FDO HERE

STAY CONNECTED

Facebook logo Twitter YouTubeLinkedIn Google + icon

ishn infographics

2012 US workplace deathsCheck out ISHN's new Infographic page! Learn more about worker safety through these interactive images. CLICK HERE to view the page.